CancerAlterome

By Gene & By Cancer:

  • You can search the CancerAlterome from the "By Gene" or "By Cancer" pages by selecting a specific gene or cancer from the auto-completion drop-down boxes.
  • You can use the bar chart to visually observe the number of gene-cancer associations in the search results.
  • You can further observe all reported gene alterations and downstream regulated biological processes in that gene-cancer search by clicking on the specific bar in the bar chart. These biological processes are normalized to the GO or HPO concept.
  • You can observe all highlighted sentence support related to the query in the table below and further filter by the search box.
  • You can download all the search results by clicking the "Download Sentences for this Gene" or "Download Sentences for this Cancer" button.

By Gene Set & By Cancer Set:

  • You can enter a specific set of genes to search in CancerAlterome and automatically draw a heat map of "Cancer-downstream biological processes regulation".
  • You can hover over the heat map to check the number of a specific "cancer-downstream biological process regulation" reported in CancerAlterome.
  • You can automatically query all the literature evidence support by clicking on any cell in the heat map and update it in the table below.
  • You can download all the search results by clicking the "Download Sentences for this Gene" or "Download Sentences for this Cancer" button.