Key Features

Customized Biomarker Regulatory Event Templates

Our approach involves using specially designed templates to identify AD-specific biomarker regulatory events from literature. This ensures the extraction of high-quality, precise information relevant to AD pathology.

Comprehensive Database

The AD-Alterome database is a specialized repository for AD, providing a centralized location for researchers to access and explore relevant data. This database supports efficient data retrieval, evidence display, and results visualization.

Functional Modules

• Single/Multi-Gene Investigation:

  Researchers can quickly search for biomarker regulatory event descriptions associated with genes of interest. Each event is backed by literature support, facilitating targeted research.

• Phenotype/Gene Recommendation:

  Utilizing a specific recommendation algorithm, this module accelerates the prioritization of AD-specific gene-phenotype associations. It also provides the necessary evidence to support these associations, streamlining the research process.

• Gene-Set Enrichment Analysis:

  Based on the hypergeometric test algorithm, this feature allows for the investigation of AD-specific gene function enrichment. It reveals potential functional associations, aiding in the understanding of AD pathology.