627 | BDNF | GO:0006954 | inflammatory response | point mutations | Association | 30477087 | Neurodegenerative disorders are caused by multiple factors, such as the accumulation of misfolded proteins, the depletion of endogenous antioxidant enzyme activity, mitochondrial dysfunction, and the deficiency of neurotrophin brain-derived neurotrophic factor (BDNF), neuro-inflammation, as well as various genetic mutations. |
627 | BDNF | GO:0006954 | inflammatory response | point mutations | Association | 30759363 | Moreover, the BDNF Val66Met mutation has been shown to be associated with CICI and might be linked with cognitive depression associated with inflammation in breast cancer survivors. |