AD-PNRLE

AD-Pathological Network with Rich Literature Evidence

Subtype-Specific

 Subtype Select

The beginning of the pathology link:


The ending of the pathological link:

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Brief description

The "1" query starting gene(s) is/are "APP", and the "1" query ending concept(s) is/are "Apoptosis of neurons".
The results of the AD-PNRLE are as follows:

1. A total of 76 pathways are retrieved, with an average length of 6.0 for each pathway.

2. A total of 1 literature are retrieved related to the query gene(s), with an average of 0.0 texts for each pathway.

3. There are 1 mutations directly associated with the query gene(s). Among them, mutation "APP:missense mutations" is related to the most pathway, with 1.

4. There are 4 biological process terms, 3 phenotypic symptom terms, and 0 diseases associated with the query gene(s). The most frequently reported biological process term is "Apoptosis of neurons" (1 times), the phenotypic symptom term is "Cerebral Amyloid Angiopathy" (1 times), and the disease is "None" (0 times) .

5. There are 0 genes linked to the query gene(s) by mutations and other biomarker.

Entrez Symbol Mutation Term ID Term Name PathwayLength
351 APP 351:Var-nonsynonymous mutation GO:0051402 Apoptosis of neurons 6
351 APP 351:Var-nonsynonymous mutation GO:0051402 Apoptosis of neurons 6
351 APP 351:Var-nonsynonymous mutation GO:0051402 Apoptosis of neurons 6
351 APP 351:Var-nonsynonymous mutation GO:0051402 Apoptosis of neurons 6
351 APP 351:Var-nonsynonymous mutation GO:0051402 Apoptosis of neurons 6
351 APP 351:Var-nonsynonymous mutation GO:0051402 Apoptosis of neurons 6
351 APP 351:Var-nonsynonymous mutation GO:0051402 Apoptosis of neurons 6
351 APP 351:Var-nonsynonymous mutation GO:0051402 Apoptosis of neurons 6
351 APP 351:Var-nonsynonymous mutation GO:0051402 Apoptosis of neurons 6
351 APP 351:Var-nonsynonymous mutation GO:0051402 Apoptosis of neurons 6
351 APP 351:Var-nonsynonymous mutation GO:0051402 Apoptosis of neurons 6
351 APP 351:Var-nonsynonymous mutation GO:0051402 Apoptosis of neurons 6
351 APP 351:Var-nonsynonymous mutation GO:0051402 Apoptosis of neurons 6
351 APP 351:Var-nonsynonymous mutation GO:0051402 Apoptosis of neurons 6
351 APP 351:Var-nonsynonymous mutation GO:0051402 Apoptosis of neurons 6
351 APP 351:Var-nonsynonymous mutation GO:0051402 Apoptosis of neurons 6
351 APP 351:Var-nonsynonymous mutation GO:0051402 Apoptosis of neurons 6
351 APP 351:Var-nonsynonymous mutation GO:0051402 Apoptosis of neurons 6
351 APP 351:Var-nonsynonymous mutation GO:0051402 Apoptosis of neurons 6
351 APP 351:Var-nonsynonymous mutation GO:0051402 Apoptosis of neurons 6
351 APP 351:Var-nonsynonymous mutation GO:0051402 Apoptosis of neurons 6
351 APP 351:Var-nonsynonymous mutation GO:0051402 Apoptosis of neurons 6
351 APP 351:Var-nonsynonymous mutation GO:0051402 Apoptosis of neurons 6
351 APP 351:Var-nonsynonymous mutation GO:0051402 Apoptosis of neurons 6
351 APP 351:Var-nonsynonymous mutation GO:0051402 Apoptosis of neurons 6
351 APP 351:Var-nonsynonymous mutation GO:0051402 Apoptosis of neurons 6
351 APP 351:Var-nonsynonymous mutation GO:0051402 Apoptosis of neurons 6
351 APP 351:Var-nonsynonymous mutation GO:0051402 Apoptosis of neurons 6
351 APP 351:Var-nonsynonymous mutation GO:0051402 Apoptosis of neurons 6
351 APP 351:Var-nonsynonymous mutation GO:0051402 Apoptosis of neurons 6
351 APP 351:Var-nonsynonymous mutation GO:0051402 Apoptosis of neurons 6
351 APP 351:Var-nonsynonymous mutation GO:0051402 Apoptosis of neurons 6
351 APP 351:Var-nonsynonymous mutation GO:0051402 Apoptosis of neurons 6
351 APP 351:Var-nonsynonymous mutation GO:0051402 Apoptosis of neurons 6
351 APP 351:Var-nonsynonymous mutation GO:0051402 Apoptosis of neurons 6
351 APP 351:Var-nonsynonymous mutation GO:0051402 Apoptosis of neurons 6
351 APP 351:Var-nonsynonymous mutation GO:0051402 Apoptosis of neurons 6
351 APP 351:Var-nonsynonymous mutation GO:0051402 Apoptosis of neurons 6
351 APP 351:Var-nonsynonymous mutation GO:0051402 Apoptosis of neurons 6
351 APP 351:Var-nonsynonymous mutation GO:0051402 Apoptosis of neurons 6
351 APP 351:Var-nonsynonymous mutation GO:0051402 Apoptosis of neurons 6
351 APP 351:Var-nonsynonymous mutation GO:0051402 Apoptosis of neurons 6
351 APP 351:Var-nonsynonymous mutation GO:0051402 Apoptosis of neurons 6
351 APP 351:Var-nonsynonymous mutation GO:0051402 Apoptosis of neurons 6
351 APP 351:Var-nonsynonymous mutation GO:0051402 Apoptosis of neurons 6
351 APP 351:Var-nonsynonymous mutation GO:0051402 Apoptosis of neurons 6
351 APP 351:Var-nonsynonymous mutation GO:0051402 Apoptosis of neurons 6
351 APP 351:Var-nonsynonymous mutation GO:0051402 Apoptosis of neurons 6
351 APP 351:Var-nonsynonymous mutation GO:0051402 Apoptosis of neurons 6
351 APP 351:Var-nonsynonymous mutation GO:0051402 Apoptosis of neurons 6
351 APP 351:Var-nonsynonymous mutation GO:0051402 Apoptosis of neurons 6
351 APP 351:Var-nonsynonymous mutation GO:0051402 Apoptosis of neurons 6
351 APP 351:Var-nonsynonymous mutation GO:0051402 Apoptosis of neurons 6
351 APP 351:Var-nonsynonymous mutation GO:0051402 Apoptosis of neurons 6
351 APP 351:Var-nonsynonymous mutation GO:0051402 Apoptosis of neurons 6
351 APP 351:Var-nonsynonymous mutation GO:0051402 Apoptosis of neurons 6
351 APP 351:Var-nonsynonymous mutation GO:0051402 Apoptosis of neurons 6
351 APP 351:Var-nonsynonymous mutation GO:0051402 Apoptosis of neurons 6
351 APP 351:Var-nonsynonymous mutation GO:0051402 Apoptosis of neurons 6
351 APP 351:Var-nonsynonymous mutation GO:0051402 Apoptosis of neurons 6
351 APP 351:Var-nonsynonymous mutation GO:0051402 Apoptosis of neurons 6
351 APP 351:Var-nonsynonymous mutation GO:0051402 Apoptosis of neurons 6
351 APP 351:Var-nonsynonymous mutation GO:0051402 Apoptosis of neurons 6
351 APP 351:Var-nonsynonymous mutation GO:0051402 Apoptosis of neurons 6
351 APP 351:Var-nonsynonymous mutation GO:0051402 Apoptosis of neurons 6
351 APP 351:Var-nonsynonymous mutation GO:0051402 Apoptosis of neurons 6
351 APP 351:Var-nonsynonymous mutation GO:0051402 Apoptosis of neurons 6
351 APP 351:Var-nonsynonymous mutation GO:0051402 Apoptosis of neurons 6
351 APP 351:Var-nonsynonymous mutation GO:0051402 Apoptosis of neurons 6
351 APP 351:Var-nonsynonymous mutation GO:0051402 Apoptosis of neurons 6
351 APP 351:Var-nonsynonymous mutation GO:0051402 Apoptosis of neurons 6
351 APP 351:Var-nonsynonymous mutation GO:0051402 Apoptosis of neurons 6
351 APP 351:Var-nonsynonymous mutation GO:0051402 Apoptosis of neurons 6
351 APP 351:Var-nonsynonymous mutation GO:0051402 Apoptosis of neurons 6
351 APP 351:Var-nonsynonymous mutation GO:0051402 Apoptosis of neurons 6
351 APP 351:Var-nonsynonymous mutation GO:0051402 Apoptosis of neurons 6