AD-PNRLE

AD-Pathological Network with Rich Literature Evidence

Gene Query

Browser style

Abstract Summary

The query genes is/are MAPT. The results of the AD-PNRLE are as follows:

1. A total of 7 literature are retrieved related to the query gene(s), with an average of 7.

2. There are 2 mutations directly associated with the query gene(s). Among them, mutation "MAPT:rs63751273" is related to the most GO terms, with 5.

3. There are 7 biological process terms, 0 phenotypic symptom terms, and 0 diseases associated with the query gene(s). The most frequently reported biological process term is "Biological regulation" (4 times), the phenotypic symptom term is "None" (0 times), and the disease is "None" (0 times).

4. There are 11 genes linked to the query gene(s) by mutations and descriptors.

Entrez Symbol Mutation Relation Term ID Term Name Count
4137 MAPT rs63751273 PosReg GO:0005153 IL6:Interleukin-8 receptor binding 1
4137 MAPT rs63751273 NegReg GO:0065007 GABRG2:Biological regulation 1
4137 MAPT rs63751273 NegReg GO:0004902 TLR7:Granulocyte colony-stimulating factor receptor activity 1
4137 MAPT rs63751273 NegReg GO:0005488 PTPA:Binding 1
4137 MAPT rs63751273 NegReg GO:0065007 GABRB2:Biological regulation 1
4137 MAPT rs63751273 NegReg GO:0065007 GABBR1:Biological regulation 1
4137 MAPT rs143624519 PosReg GO:0007268 CA3:Chemical synaptic transmission 1
5534 PPP3R1 rs1868402 PosReg GO:0016310 MAPT:Phosphorylation 1
4137 MAPT rs63751273 NegReg GO:0065007 GABRB3:Biological regulation 1
2932 GSK3B rs6438552 PosReg GO:0016310 MAPT:Phosphorylation 1
4137 MAPT rs63751273 NegReg GO:0030150 PRKN:Protein import into mitochondrial matrix 1