AD-Pathological Network with Rich Literature Evidence

GO Query


Brief description

The query term(s) is/are inflammatory response. The results of the AD-PNRLE are as follows:

1. A total of 7 literature are retrieved related to the query gene(s), with an average of 7.

2. There are 6 mutations directly associated with the query gene(s). Among them, mutation "TREM2:rs75932628" is related to the most GO terms, with 1.

3. There are 1 biological process terms, 0 phenotypic symptom terms, and 0 diseases associated with the query gene(s). The most frequently reported biological process term is "Inflammatory response" (1 times), the phenotypic symptom term is "None" (0 times), and the disease is "None" (0 times).

4. There are 5 genes linked to the query gene(s) by mutations and descriptors.

Entrez Symbol Mutation Relation Term ID Term Name Evidence Table
43 ACHE rs17228602 Negative regulation GO:0006954 Inflammatory response Jump
627 BDNF rs6265 Association GO:0006954 Inflammatory response Jump
120892 LRRK2 rs34637584 Positive regulation GO:0006954 Inflammatory response Jump
6622 SNCA rs104893877 Negative regulation GO:0006954 Inflammatory response Jump
54209 TREM2 rs75932628 Association GO:0006954 Inflammatory response Jump
3635 INPP5D rs61068452 Association GO:0006954 Inflammatory response Jump
54209 TREM2 rs75932628 Negative regulation GO:0006954 Inflammatory response Jump